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Volunteers needed to try a 2 day treatment for recurrent genital herpes

Summary A randomised double-blind multi-centre study to assess the efficacy and safety of self-initiated short course (two-day) oral Famciclovir therapy for active recurring genital herpes
 

Who can participate

Anyone who experiences at least three recurrences of genital herpes infection per year will be recruited. If eligible you will be randomly assigned to one of the two treatment groups prior to each recurrence and will be given a study kit to take home. You will be randomly assigned to either a two-day treatment with Famciclovir 500 mg initial dose, followed by 250 mg 12 hours later, or a standard five-day treatment with Famciclovir 125 mg given every 12 hours.

What to expect

After initiating therapy you will be required to return to the clinic within 24 hours for a clinical assessment to confirm the recurrence. You will complete two questionnaires to evaluate various aspects of symptoms and functions. You will be required to return to the clinic for one follow-up visit on the day of completion of the five days of study medication. At this time the state of lesion healing will be assessed You will then be re-randomised for a new course of double-blind study medication to be used for a second recurrence of genital herpes and the process repeated.

Contact phone     02 8752 4350
Contact email     research@fpahealth.org.au
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URL: http://www.fpnsw.org.au/research/projects/FaST_20040505.html
Last Modified: Monday, 14-Apr-2008 15:25:25 EST
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